Novel non-invasive contrast agents for virtual histology and 3D quantification of soft tissues

Rapid Virtual Histology in 3D for Cartilage, Soft tissue, Bones, Scaffolds and Cells - with novel micro and nano CT without using contrast agents

ویرتوپسی، مکملی برای اتوپسی

    Background & Aims: A utopsies are recognized as valuable medical procedures. A number of digital radiology techniques, including multislice CT, MRI, and photogrammetry with 3D surface scanning have the potential to change traditional autopsy and improve the reliability of results. Virtual Autopsy is a non-invasive procedure with no damage to the tissues. Noninvasive virtual autopsying could...

Non-invasive quantification of liver fat content by different Gradient Echo MRI sequences in patients with Non-Alcoholic Fatty Liver Disease (NAFLD)

Introduction: Non-invasive quantification of liver fat by Gradient echo (GRE) Technique is an interesting issue in quantitative MRI. Despite the numerous advantages of this technique, fat measurement maybe biased by confounding and effects. The aim of this study was to evaluate the GRE pulse sequences with different   and  weighting for liver fat quantification in patients with...

Analytical determination of the chemical exchange saturation transfer (CEST) contrast in molecular magnetic resonance imaging

Magnetic resonance based on molecular imaging allows tracing contrast agents thereby facilitating early diagnosis of diseases in a non-invasive fashion that enhances the soft tissue with high spatial resolution. Recently, the exchange of protons between the contrast agent and water, known as the chemical exchange saturation transfer (CEST) effect, has been measured by applying a suitable pulse ...

High-contrast X-ray micro-radiography and micro-CT of ex-vivo soft tissue murine organs utilizing ethanol fixation and large area photon-counting detector

Using dedicated contrast agents high-quality X-ray imaging of soft tissue structures with isotropic micrometre resolution has become feasible. This technique is frequently titled as virtual histology as it allows production of slices of tissue without destroying the sample. The use of contrast agents is, however, often an irreversible time-consuming procedure and despite the non-destructive pri...